{"id":8246,"date":"2026-03-19T09:09:54","date_gmt":"2026-03-19T09:09:54","guid":{"rendered":"https:\/\/healaxispharma.com\/?post_type=product&#038;p=8246"},"modified":"2026-04-23T10:53:46","modified_gmt":"2026-04-23T10:53:46","slug":"drotaverine-hcl-injection","status":"publish","type":"product","link":"https:\/\/healaxispharma.com\/?product=drotaverine-hcl-injection","title":{"rendered":"Drotaverine HCL Injection"},"content":{"rendered":"<h2 class=\"wp-block-heading\"><strong>What is Drotaverine HCL Injection?<\/strong><\/h2>\n<h3 class=\"wp-block-heading\"><strong>Overview<\/strong><\/h3>\n<p>Drotaverine HCL Injection is a medicine that relaxes and stops spasms in smooth muscles.<\/p>\n<p>It is mostly used to treat pain and spasms that come from different gastric, biliary, urinary, and gynecological conditions.<\/p>\n<p>As a synthetic isoquinoline, it stops phosphodiesterase-4 (PDE-4). This action helps relax smooth muscle.<\/p>\n<p>People who need immediate care often choose the injectable form because it works quickly and effectively to control moderate to severe spasmodic pain.<\/p>\n<h3 class=\"wp-block-heading\"><strong>Description<\/strong><\/h3>\n<div id=\"ilbIconList-878e4f78-3\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-arrows-turn-right\"><\/i>\n<p class=\"text\"><strong>Drug Class:<\/strong>\u00a0Isoquinoline derivative antispasmodic<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrows-turn-right\"><\/i>\n<p class=\"text\"><strong>Mode of Action:<\/strong>\u00a0Phosphodiesterase-4 inhibitor<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrows-turn-right\"><\/i>\n<p class=\"text\"><strong>Administration Route:<\/strong>\u00a0Intramuscular (IM) or slow Intravenous (IV) injection<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrows-turn-right\"><\/i>\n<p class=\"text\"><strong>Form:<\/strong>\u00a0Injectable solution, often in 2 ml ampoules with a concentration of 40 mg\/ml<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrows-turn-right\"><\/i>\n<p class=\"text\"><strong>Onset of Action:<\/strong>\u00a0Expeditious (within 5\u201310 minutes)<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrows-turn-right\"><\/i>\n<p class=\"text\"><strong>Duration of Action:<\/strong>\u00a02 to 4 hours, contingent upon the dosage and administration route<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 class=\"wp-block-heading\"><strong>Uses of Drotaverine HCL Injection<\/strong><\/h2>\n<h3 class=\"wp-block-heading\"><strong>Uses<\/strong><\/h3>\n<div id=\"ilbIconList-6136c013-c\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-arrow-right-from-bracket\"><\/i>\n<p class=\"text\"><strong>Renal colic:<\/strong>\u00a0Pain caused by kidney stones obstructing the urinary tract<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrow-right-from-bracket\"><\/i>\n<p class=\"text\"><strong>Biliary colic:<\/strong>\u00a0Pain due to gallstones or biliary tract obstruction<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrow-right-from-bracket\"><\/i>\n<p class=\"text\"><strong>Intestinal colic:<\/strong>\u00a0Cramping pain in the intestines<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrow-right-from-bracket\"><\/i>\n<p class=\"text\"><strong>Dysmenorrhea:<\/strong>\u00a0Menstrual cramps<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h3 class=\"wp-block-heading\"><strong>Indications<\/strong><\/h3>\n<p>Irritable Bowel Syndrome (IBS).<\/p>\n<p>Ureteric spasm.<\/p>\n<p>Gallbladder dysfunction.<\/p>\n<p>Gastroenteritis associated cramps.<\/p>\n<p>Endometriosis and other gynecological spasm disorders.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Drug Interactions<\/strong><\/h2>\n<div id=\"ilbIconList-1f88ec2b-c\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-arrow-right\"><\/i>\n<p class=\"text\"><strong>Levodopa:<\/strong>\u00a0Lowers the effectiveness of levodopa and may make Parkinson\u2019s symptoms worse.<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrow-right\"><\/i>\n<p class=\"text\"><strong>Anticholinergic drugs:<\/strong>\u00a0It may make the effects of antispasmodic medications and side effects worse.<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrow-right\"><\/i>\n<p class=\"text\"><strong>Antihypertensives:<\/strong>\u00a0Some of them may make the benefits of lowering blood pressure even stronger<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrow-right\"><\/i>\n<p class=\"text\"><strong>Intoxicants:<\/strong>\u00a0Alcohol and sedatives may make you more likely to get dizzy and low blood pressure.<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrow-right\"><\/i>\n<p class=\"text\"><strong>CYP450 substrates:<\/strong>\u00a0Be careful when mixing with drugs that are broken down by CYP enzymes.<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 class=\"wp-block-heading\"><strong>Benefits<\/strong><\/h2>\n<p>An immediate remedy for gynecological, renal, or abdominal spasms.<\/p>\n<p>It does not have a sedative effect, unlike other pain relievers.<\/p>\n<p>Different from other antispasmodics, there are no anticholinergic side effects.<\/p>\n<p>Intended for supervised, long-term usage in patients with chronic disorders.<\/p>\n<p>It helps those whose lives are plagued by gastrointestinal problems live better.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Side Effects<\/strong><\/h2>\n<div id=\"ilbIconList-1ab3a4f5-c\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Injection site irritation or pain<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Nausea<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Dizziness<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Headache<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Dry mouth<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Feeling of warmth or flushing<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 class=\"wp-block-heading\"><strong>Dosage Guidelines<\/strong><\/h2>\n<div id=\"ilbIconList-c885b777-d\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-star-of-life\"><\/i>\n<p class=\"text\"><strong>How to Use \/ How to Take<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p>Before you use the vial, check it for any stains or particles.<\/p>\n<p>If the manufacturer instructs, shake it.<\/p>\n<p>Clean the needles and syringes.<\/p>\n<p>Do not mix with other injectable drugs unless told to do so.<\/p>\n<p>After opening, discard any unused portion safely.<\/p>\n<div id=\"ilbIconList-5839c830-5\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-star-of-life\"><\/i>\n<p class=\"text\"><strong>Direction for Use<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p><strong>Adults:<\/strong>\u00a040\u201380 mg, each dosage administered via intramuscular or slow intravenous route, up to three times daily.<\/p>\n<p><strong>Maximum Daily Dose:<\/strong>\u00a0Typically not exceeding 240 mg.<\/p>\n<p><strong>Children:<\/strong>\u00a0Injectable form is not advised unless prescribed by a doctor.<\/p>\n<div id=\"ilbIconList-07d17c3a-5\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-star-of-life\"><\/i>\n<p class=\"text\"><strong>When Not to Use<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p>Known hypersensitivity to Drotaverine.<\/p>\n<p>Severe liver or kidney impairment.<\/p>\n<p>Cardiogenic shock or severe heart failure.<\/p>\n<p>Hypotension or severe arterial disease.<\/p>\n<h2 class=\"wp-block-heading\"><strong>How Does Drotaverine Work?<\/strong><\/h2>\n<p>Drotaverine specifically stops the enzyme phosphodiesterase-4 (PDE-4), which raises the amount of cyclic AMP (cAMP) in smooth muscle cells.<\/p>\n<p>Because of this rise in cAMP, intracellular calcium levels drop, which makes the smooth muscles soften.<\/p>\n<p>This action helps ease painful spasms, mostly in the uterus, gallbladder, intestines, and urinary system.<\/p>\n<p>Unlike anticholinergic drugs, Drotaverine doesn\u2019t affect the parasympathetic nervous system. This means that it can relax muscles without causing any side effects.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Concerns<\/strong><\/h2>\n<p>IV administration should be constantly monitored due to the danger of a sudden reduction in blood pressure.<\/p>\n<p>Long-term use should be properly overseen to avoid liver or gastrointestinal adverse effects.<\/p>\n<p>May conceal indications of significant underlying diseases. Delaying diagnosis<\/p>\n<h2 class=\"wp-block-heading\"><strong>Warnings<\/strong><\/h2>\n<p>It should be used with caution in people with low blood pressure.<\/p>\n<p>It serves not as a substitute for surgical intervention in acute obstructions.<\/p>\n<p>Avoid use throughout early pregnancy unless clearly necessary.<\/p>\n<p>Caution for people with heart rhythm abnormalities.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Precautions<\/strong><\/h2>\n<p>Watch the vital signs while the IV is being given.<\/p>\n<p>Stay away from drinking booze.<\/p>\n<p>Before using, if you are pregnant or breastfeeding, talk to your doctor.<\/p>\n<p>Not good for kids unless specifically told to do so<\/p>\n<p>Avoid operating heavy machinery post-injection<\/p>\n<h2 class=\"wp-block-heading\"><strong>Special Dietary &amp; Lifestyle Recommendations<\/strong><\/h2>\n<p>Drotaverine HCL Injection can be more successful for spasmodic pain if food and lifestyle changes are made.<\/p>\n<p>A light diet that is easy to digest and low in fat helps your gut. It has high fiber, which keeps things moving and prevents constipation.<\/p>\n<p>This can reduce cramping. Eat less hot, oily, and processed foods to avoid stomach cramps.<\/p>\n<p>In cases of urinary or kidney disease, staying hydrated helps eliminate toxins and sustain smooth muscle activity.<\/p>\n<p>Reduce coffee and alcohol intake to avoid dehydration and gastrointestinal irritation.<\/p>\n<p>Lifestyle changes, including yoga, meditation, and light exercise, can minimize stress-induced muscular spasms.<\/p>\n<p>Regular sleep and avoiding idleness improve health and minimize cramps.<\/p>\n<h2 class=\"wp-block-heading\"><strong>General Instructions<\/strong><\/h2>\n<p>Use only with medical supervision.<\/p>\n<p>Avoid self-injection or reusing needles.<\/p>\n<p>Do not combine with other injectable drugs without consultation.<\/p>\n<p>Please report any allergic reactions or negative effects promptly.<\/p>\n<p>Even if your symptoms improve, continue taking the recommended amount.<\/p>\n<h2 class=\"wp-block-heading\"><strong>What Else Can I Do to Help My Condition?<\/strong><\/h2>\n<p>In addition to Drotaverine HCL Injection, as suggested by your doctor, many supporting measures can improve your situation.<\/p>\n<p>Be sure to drink a lot of water. This helps keep your urine and stomach systems in good shape. Also, eat a balanced diet with plenty of fiber.<\/p>\n<p>It can reduce stomach spasms. Avoid hot, greasy, or\u00a0<a href=\"https:\/\/www.mayoclinic.org\/symptoms\/intestinal-gas\/basics\/causes\/sym-20050922\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" data-type=\"link\" data-id=\"https:\/\/www.mayoclinic.org\/symptoms\/intestinal-gas\/basics\/causes\/sym-20050922\">gas-producing foods<\/a>, which can increase abdominal pain.<\/p>\n<p>Relaxation practices, including deep breathing, yoga, and meditation, can reduce muscle spasms caused by stress.<\/p>\n<p>Reducing spasms via improving digestion and circulation through regular exercise. A warm compress on the lower belly and mild stretching may help ladies with menstrual cramps.<\/p>\n<p>Keeping a symptom diary might help you monitor your health. Also, attending follow-up appointments is important.<\/p>\n<p>Discussing any changes with your doctor can personalize your treatment. This all leads to better outcomes.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Comparison with Other Treatments<\/strong><\/h2>\n<p>Hyoscine (Buscopan) has more anticholinergic side effects, such as dry mouth and blurred vision. If you are sensitive to these effects, Drotaverine is a better choice.<\/p>\n<p><a href=\"https:\/\/www.actizapharma.com\/product\/drotaverine-hcl\/\" data-type=\"link\" data-id=\"https:\/\/www.actizapharma.com\/product\/drotaverine-hcl\/\">Drotaverine<\/a>\u00a0works faster than Mebeverine and treats more conditions. In contrast, Mebeverine is mainly for IBS and takes longer to kick in.<\/p>\n<p>NSAIDs may ease pain, but they don\u2019t stop muscle cramps. Drotaverine goes after the real problem, which is muscle tension.<\/p>\n<p>Papaverine and Drotaverine both work in similar ways, but Drotaverine is stronger, better accepted, and lasts longer.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Can I Use It With Other Medications?<\/strong><\/h2>\n<p>Antibiotics (for infections causing spasms).<\/p>\n<p>Antacids and proton pump inhibitors.<\/p>\n<p>NSAIDs for additional pain relief.<\/p>\n<p>Antiemetics like domperidone.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Storage Information<\/strong><\/h2>\n<p>Maintain storage at temperatures below 25\u00b0C<\/p>\n<p>Shield against illumination and humidity<\/p>\n<p>Retain in original packaging<\/p>\n<p>Refrain from freezing<\/p>\n<p>Maintain out of children\u2019s reach<\/p>\n<p>Safely dispose of unused solution<\/p>\n","protected":false},"excerpt":{"rendered":"<table class=\"shop_attributes table mt-2 align-middle\">\n<tbody>\n<tr>\n<th class=\"table-light\">Product\/Composition:-<\/th>\n<td class=\"p-2\"><em>Drotaverine HCL Injection<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Strength:-<\/th>\n<td class=\"p-2\"><em>40mg, 80mg<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Form:-<\/th>\n<td class=\"p-2\"><em>Injection<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Production Capacity:-<\/th>\n<td class=\"p-2\"><em>1 Million Injection\/Month<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Therapeutic use:-<\/th>\n<td class=\"p-2\"><em>Analgesic<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Package Insert\/Leaflet:-<\/th>\n<td class=\"p-2\"><em>Available upon request<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":8248,"comment_status":"open","ping_status":"closed","template":"","meta":{"inline_featured_image":false},"product_brand":[],"product_cat":[15,89,105],"product_tag":[],"class_list":{"0":"post-8246","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-all-medicine","7":"product_cat-analgesics-medicine","8":"product_cat-injection","10":"first","11":"instock","12":"shipping-taxable","13":"product-type-simple"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/healaxispharma.com\/index.php?rest_route=\/wp\/v2\/product\/8246","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healaxispharma.com\/index.php?rest_route=\/wp\/v2\/product"}],"about":[{"href":"https:\/\/healaxispharma.com\/index.php?rest_route=\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8246"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=\/wp\/v2\/media\/8248"}],"wp:attachment":[{"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8246"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_brand&post=8246"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_cat&post=8246"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_tag&post=8246"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}