{"id":8439,"date":"2026-03-23T10:05:58","date_gmt":"2026-03-23T10:05:58","guid":{"rendered":"https:\/\/healaxispharma.com\/?post_type=product&#038;p=8439"},"modified":"2026-04-23T10:53:41","modified_gmt":"2026-04-23T10:53:41","slug":"ceftriaxone-sodium-injection","status":"publish","type":"product","link":"https:\/\/healaxispharma.com\/?product=ceftriaxone-sodium-injection","title":{"rendered":"Ceftriaxone Sodium Injection"},"content":{"rendered":"<h2 class=\"wp-block-heading\"><strong>What is Ceftriaxone Sodium Injection?<\/strong><\/h2>\n<p>The broad-spectrum third-generation cephalosporin antibiotic Ceftriaxone Sodium Injection is used to treat a number of serious bacterial illnesses.<\/p>\n<p>With medical care, it is given through an IV or an IM (intramuscular) route.<\/p>\n<p>Because it has a long half-life and kills bacteria very effectively, it is very useful in hospitals and other clinical situations for treating moderate to severe infections.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Overview<\/strong><\/h2>\n<div id=\"ilbIconList-5e13492b-9\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-angles-right\"><\/i>\n<p class=\"text\"><strong>Drug Class:<\/strong>\u00a0Cephalosporin Antibiotic (3rd Generation)<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-angles-right\"><\/i>\n<p class=\"text\"><strong>Route of Administration:<\/strong>\u00a0IV (intravenous), IM (intramuscular)<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-angles-right\"><\/i>\n<p class=\"text\"><strong>Activity Spectrum:<\/strong>\u00a0Broad-spectrum (Gram-positive and Gram-negative bacteria)<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-angles-right\"><\/i>\n<p class=\"text\"><strong>Molecular Formula:<\/strong>\u00a0C18H18N8Na2O7S3\u00b73.5H2O<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 class=\"wp-block-heading\"><strong>Description<\/strong><\/h2>\n<p>Ceftriaxone is a semi-synthetic antibiotic that is clean and is made from cephalosporin C.<\/p>\n<p>It comes in single-use vials that need to be reconstituted before they can be used.<\/p>\n<p>It is given as a sodium salt that may be injected.Bacteria are killed by the drug because it stops bacteria from making cell walls.<\/p>\n<p>Ceftriaxone has a longer half-life (up to 8 hours), which means it only needs to be taken once a day.<\/p>\n<p>This makes it easier for patients to follow their treatment plans and for doctors to do their jobs more efficiently.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Uses \/ Indications<\/strong><\/h2>\n<p>Infections of the lower respiratory system, like pneumonia and bronchitis.<\/p>\n<p>Urinary tract diseases, such as pyelonephritis. Infections of the skin and soft tissues.<\/p>\n<p>Infections inside the abdomen. Sepsis caused by bacteria. Diseases of the bones and joints.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Benefits<\/strong><\/h2>\n<p>Strong antibacterial action against both Gram-negative and Gram-positive bacteria across a broad spectrum<\/p>\n<p>The once-daily dose is supported by the long half-life.<\/p>\n<p>Able to penetrate deeply into the tissues and fluids of the body, particularly the cerebrospinal fluid<\/p>\n<p>Utilizable in the treatment of severe and potentially fatal infections<\/p>\n<h2 class=\"wp-block-heading\"><strong>Side Effects<\/strong><\/h2>\n<h3 class=\"wp-block-heading\"><strong>Common Side Effects:<\/strong><\/h3>\n<div id=\"ilbIconList-4dba9de8-e\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Local reactions at the injection site<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Diarrhea<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Nausea or vomiting<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Rash or allergic skin reactions<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Elevated liver enzymes<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Eosinophilia<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h3 class=\"wp-block-heading\"><strong>Less Common \/ Serious:<\/strong><\/h3>\n<div id=\"ilbIconList-0b570e1a-2\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Anaphylaxis or severe hypersensitivity reactions<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Clostridioides difficile-associated diarrhea (CDAD)<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Hemolytic anemia<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Nephrotoxicity<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-dot\"><\/i>\n<p class=\"text\">Hepatotoxicity<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 class=\"wp-block-heading\"><strong>How Does It Work?<\/strong><\/h2>\n<p>Penicillin-binding proteins (PBPs) inside bacterial cell walls are what ceftriaxone does.<\/p>\n<p>It stops these proteins from working. These proteins are needed to make peptidoglycan, which is what gives the cell wall of bacteria its shape.<\/p>\n<p>By blocking PBPs, the wall formation is thrown off, which breaks down cells and kills the germs. In this way, ceftriaxone kills bacteria.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Dosage Guidelines \/ How to Use<\/strong><\/h2>\n<div id=\"ilbIconList-cc990c34-6\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-arrow-right\"><\/i>\n<p class=\"text\"><strong>Adults (general infections):<\/strong>\u00a01\u20132 g once daily IV or IM.<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-arrow-right\"><\/i>\n<p class=\"text\"><strong>Severe infections:<\/strong>\u00a0Up to 4 grams a day in split dosages.<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-arrow-right\"><\/i>\n<p class=\"text\"><strong>Uncomplicated gonorrhea:<\/strong>\u00a0Single 250\u2013500 mg IM dose.<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-arrow-right\"><\/i>\n<p class=\"text\"><strong>Bacterial meningitis (adults):<\/strong>\u00a02 g IV every 12 hours.<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-circle-arrow-right\"><\/i>\n<p class=\"text\"><strong>Children (above 28 days):<\/strong>\u00a050\u2013100 mg\/kg once daily (max 2 g\/day).<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 class=\"wp-block-heading\"><strong>When Not to Use<\/strong><\/h2>\n<p>Known hypersensitivity to ceftriaxone and other cephalosporins.<\/p>\n<p>Neonates with hyperbilirubinemia or jaundice (risk for kernicterus).<\/p>\n<p>Neonates get calcium-containing IV solutions (risk of precipitation).<\/p>\n<p>Severe hepatic and renal dysfunction without dosage adjustment.<\/p>\n<p>A history of having very bad allergic responses to beta-lactam drugs.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Drug Interactions<\/strong><\/h2>\n<p>Ceftriaxone may interact with other drugs, affecting its efficacy or risking unwanted effects.<\/p>\n<p>Calcium-containing IV solutions can cause life-threatening lung and renal precipitations in neonates, making them a critical interaction.<\/p>\n<p>When taken with aminoglycosides like\u00a0<a href=\"https:\/\/www.actizapharma.com\/product\/gentamicin\/\" data-type=\"link\" data-id=\"https:\/\/www.actizapharma.com\/product\/gentamicin\/\">gentamicin<\/a>, Nephrotoxicity is increased; hence, kidney function should be monitored.<\/p>\n<p>Sequential usage of loop diuretics like furosemide may raise kidney injury risk.<\/p>\n<p>Ceftriaxone can increase bleeding risk from oral anticoagulants like warfarin and reduce oral contraceptive efficacy by affecting gut flora.<\/p>\n<p>By suppressing renal excretion, probenecid prolongs ceftriaxone\u2019s action.<\/p>\n<p>Therefore, before starting ceftriaxone, doctors must know about all current drugs to avoid dangerous interactions.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Safety Advice<\/strong><\/h2>\n<p>Do not use without expert supervision.<\/p>\n<p>Finish the whole course to avoid resistance.<\/p>\n<p>Notice how the liver and kidneys work during long-term or high-dose treatment.<\/p>\n<p>Watch out for signs of allergic responses, such as rashes, swelling, and trouble breathing.<\/p>\n<p>Report any serious\u00a0<a href=\"https:\/\/medlineplus.gov\/diarrhea.html#:~:text=Diarrhea%20is%20loose%2C%20watery%20stools,but%20it%20may%20last%20longer.\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" data-type=\"link\" data-id=\"https:\/\/medlineplus.gov\/diarrhea.html#:~:text=Diarrhea%20is%20loose%2C%20watery%20stools,but%20it%20may%20last%20longer.\">diarrhea\u00a0<\/a>or stomach pain that could be caused by C. difficile.<\/p>\n<p>Change the amount for people who have problems with their kidneys or liver.<\/p>\n<h2 class=\"wp-block-heading\"><strong>General Instructions<\/strong><\/h2>\n<p>Always be sure that a qualified medical practitioner is in charge of it.<\/p>\n<p>Do not self-administer the medication or make any adjustments to the dosage on your own.<\/p>\n<p>You shouldn\u2019t stop all of a sudden, even if the signs get better.<\/p>\n<p>Prepare the answer from scratch, and if feasible, utilize it right away.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Dietary &amp; Lifestyle Recommendations<\/strong><\/h2>\n<p>While taking Ceftriaxone Injection, make sure you eat a healthy, well-balanced diet that is full of nutrients to help your immune system and speed up your healing.<\/p>\n<p>Stay hydrated, especially if you have a fever or are weary after an illness.<\/p>\n<p>If your doctor tells you to, adding probiotics like yogurt or fermented foods to your diet may help stop diarrhea caused by antibiotics.<\/p>\n<p>If you are getting treatment, don\u2019t drink booze.<\/p>\n<p>It can hurt your liver and make side effects worse.<\/p>\n<p>Do not use other medicines or diarrhea-busting drugs on your own unless your doctor tells you to.<\/p>\n<p>Lastly, get enough rest and don\u2019t overdo it with physical activity to help the body heal.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Comparison with Other Antibiotics<\/strong><\/h2>\n<p>The broad-spectrum activity and once-daily dose of third-generation cephalosporin ceftriaxone make it more convenient than other antibiotics.<\/p>\n<p>Unlike amoxicillin, which targets gram-positive organisms and requires numerous doses per day, ceftriaxone works against both gram-positive and gram-negative bacteria and is acceptable for more severe infections.<\/p>\n<p>Ceftriaxone is safer than ciprofloxacin, a fluoroquinolone with strong gram-negative coverage, especially in children and the elderly.<\/p>\n<p>Mercopenem, a carbapenem, is used in critical care and has a wider scope for resistant infections but requires more frequent doses.<\/p>\n<p>Ceftriaxone is chosen for many systemic infections due to its efficacy, safety, and convenience.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Precautions &amp; Warnings<\/strong><\/h2>\n<p>Be careful when giving this to people who have had an allergic reaction to penicillin in the past.<\/p>\n<p>Keep an eye out for superinfections, especially when fungi develop too much.<\/p>\n<p>It could lead to false positives in the Coombs test and glucose urine tests.<\/p>\n<p><strong>Pregnancy:<\/strong>\u00a0Category B\u2014no known danger, but only use if you really need to.<\/p>\n<p><strong>Breastfeeding:<\/strong>\u00a0Small amounts may get into the milk, so be careful.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Can It Be Used with Other Medications?<\/strong><\/h2>\n<h3 class=\"wp-block-heading\"><strong>It can be used with<\/strong><\/h3>\n<div id=\"ilbIconList-6828b9e3-a\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fas fa-check-square\"><\/i>\n<p class=\"text\">Paracetamol<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fas fa-check-square\"><\/i>\n<p class=\"text\">Non-calcium IV fluids<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fas fa-check-square\"><\/i>\n<p class=\"text\">Antipyretics<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fas fa-check-square\"><\/i>\n<p class=\"text\">Antiemetics<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h3 class=\"wp-block-heading\"><strong>Avoid combining with:<\/strong><\/h3>\n<div id=\"ilbIconList-a1465e63-8\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-regular fa-circle-stop\"><\/i>\n<p class=\"text\">Calcium-containing IV fluids<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-regular fa-circle-stop\"><\/i>\n<p class=\"text\">Strong diuretics<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-regular fa-circle-stop\"><\/i>\n<p class=\"text\">Other nephrotoxic drugs<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-regular fa-circle-stop\"><\/i>\n<p class=\"text\">Aminoglycosides<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-regular fa-circle-stop\"><\/i>\n<p class=\"text\">Antacids<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 class=\"wp-block-heading\"><strong>Storage<\/strong><\/h2>\n<p>Unopened vials should be stored at a temperature between 20\u00b0C and 25\u00b0C, and they should be shielded from light and moisture.<\/p>\n<p>At ambient temperature, it remains stable for six hours.<\/p>\n<p>Stable for 24 hours when refrigerated at 2\u00b0C\u20138\u00b0C IM solutions containing lidocaine should not be administered intravenously.<\/p>\n<p>If you can see particles or color changes, throw it away.<\/p>\n","protected":false},"excerpt":{"rendered":"<table class=\"shop_attributes table mt-2 align-middle\">\n<tbody>\n<tr>\n<th class=\"table-light\">Product\/Composition:-<\/th>\n<td class=\"p-2\"><em>Ceftriaxone Sodium<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Strength:-<\/th>\n<td class=\"p-2\"><em>1000mg, 250mg<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Form:-<\/th>\n<td class=\"p-2\"><em>Injection<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Production Capacity:-<\/th>\n<td class=\"p-2\"><em>1 Million Injection\/Month<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Therapeutic use:-<\/th>\n<td class=\"p-2\"><em>Anti biotic\/ Anti infective\/ Anti fungal<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Package Insert\/Leaflet:-<\/th>\n<td class=\"p-2\"><em>Available upon request<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"inline_featured_image":false},"product_brand":[],"product_cat":[15,90,108],"product_tag":[157],"class_list":{"0":"post-8439","1":"product","2":"type-product","3":"status-publish","5":"product_cat-all-medicine","6":"product_cat-anti-biotic-anti-infective-anti-fungal","7":"product_cat-injection-anti-biotic-anti-infective-anti-fungal","8":"product_tag-injection","10":"first","11":"instock","12":"shipping-taxable","13":"product-type-simple"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/healaxispharma.com\/index.php?rest_route=\/wp\/v2\/product\/8439","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healaxispharma.com\/index.php?rest_route=\/wp\/v2\/product"}],"about":[{"href":"https:\/\/healaxispharma.com\/index.php?rest_route=\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8439"}],"wp:attachment":[{"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8439"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_brand&post=8439"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_cat&post=8439"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_tag&post=8439"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}