{"id":8681,"date":"2026-04-08T09:36:52","date_gmt":"2026-04-08T09:36:52","guid":{"rendered":"https:\/\/healaxispharma.com\/?post_type=product&#038;p=8681"},"modified":"2026-04-23T10:53:16","modified_gmt":"2026-04-23T10:53:16","slug":"gemcitabine-hydrochloride-injection","status":"publish","type":"product","link":"https:\/\/healaxispharma.com\/?product=gemcitabine-hydrochloride-injection","title":{"rendered":"Gemcitabine Hydrochloride Injection"},"content":{"rendered":"<h2 class=\"wp-block-heading\"><strong>What is Gemcitabine Hydrochloride Injection?<\/strong><\/h2>\n<p>Gemcitabine Hydrochloride Injection is a drug used to treat cancer. It is an antimetabolite drug.<\/p>\n<p>These are drugs that inhibit or slow down the division and growth of cancer cells.<\/p>\n<p>Gemcitabine is infused into the body intravenously via a drip in clinics or hospitals.<\/p>\n<p>It is usually prescribed for pancreatic, lung, breast, bladder, and ovarian cancers.<\/p>\n<p>Doctors prescribe this medication to delay or shrink tumours.<\/p>\n<p>It is usually used in conjunction with other other chemotherapeutic agents.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Overview<\/strong><\/h2>\n<p>Gemcitabine does this by incorporating it into cancer cells and stopping them from making new DNA.<\/p>\n<p>Without a means to grow or fix themselves, cancer cells perish. This medication isn\u2019t given at home.<\/p>\n<p>A doctor must give it. Patients are given the drug most often once weekly or every few weeks, depending on the disease they have.<\/p>\n<p>Treatment length depends on the type of cancer and the patient\u2019s response.<\/p>\n<p>They have blood drawn regularly to check for side effects and how well the drug is progressing.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Description<\/strong><\/h2>\n<p>Gemcitabine comes in powder form that is mixed with liquid before being given through an infusion.<\/p>\n<p>It is slowly administered over 30 minutes into a vein. The dosage is determined on the body\u2019s size and the kind of tumor.<\/p>\n<p>It can be single or in combination with other chemotherapy drugs.<\/p>\n<p>Blood tests and kidney and liver function tests are checked by physicians every time a dose is given.<\/p>\n<p>This keeps patients from getting sick and stops low blood cells or organ damage.<\/p>\n<p>The medicine will be colourless or pale yellow once it has been prepared.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Uses \/ Indications<\/strong><\/h2>\n<p>Gemcitabine is used differently depending on the type of cancer.<\/p>\n<p>In pancreatic cancer, it is usually used alone as a first-line treatment.<\/p>\n<p>In lung cancer, it is commonly used along with another drug like cisplatin.<\/p>\n<p>It is used in combination with other chemotherapy drugs for ovarian and breast cancer.<\/p>\n<p>In bladder cancer, it can be used if other methods do not respond well.<\/p>\n<p>Doctors also use it to treat bile duct cancer and testicular cancer when other treatments do not work.<\/p>\n<p>Its use is properly planned by teams of cancer treatment professionals.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Benefits<\/strong><\/h2>\n<p>The main benefit of Gemcitabine is that it slows down or stops cancer cells growing.<\/p>\n<p>It can shrink tumours, relieve symptoms like pain or blockage, and extend life.<\/p>\n<p>In pancreatic cancer patients, it can make them function better and feel good during treatment.<\/p>\n<p>When combined with other drugs in chemotherapy, it improves the success rate of shrinking or postponing the return of tumours.<\/p>\n<p>It is also beneficial in a case where the cancer has recurred after other therapies.<\/p>\n<p>The patient can have fewer side effects compared to undergoing some of the older chemotherapies.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Side Effects<\/strong><\/h2>\n<div id=\"ilbIconList-e58a6b2c-f\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-brands fa-artstation\"><\/i>\n<p class=\"text\"><strong>Common Side Effects:<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p>Weakness or tiredness is experienced by most patients following the administration of Gemcitabine.<\/p>\n<p>Nausea, vomiting, and anorexia are also common results.<\/p>\n<p>Flu-like reactions with fever, chills, and muscle pain in some people. Hair thinning, skin rash, or sore mouth are also felt.<\/p>\n<p>They are temporary and mild side effects that cease once the infusion is discontinued.<\/p>\n<div id=\"ilbIconList-4d38f1c0-1\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-brands fa-artstation\"><\/i>\n<p class=\"text\"><strong>Hematological Side Effects:<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p>This medication can lower the blood cell counts. Red cell levels drop, resulting in anaemia and tiredness.<\/p>\n<p>Low white cell counts raise the risk of infection. Bruising or bleeding easily may be caused by a low platelet count.<\/p>\n<p>Before each dose, blood tests are done to check for any of these counts.<\/p>\n<p>When they drop too low, the doctor can postpone the next treatment or reduce the dosage.<\/p>\n<div id=\"ilbIconList-515a362f-d\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-brands fa-artstation\"><\/i>\n<p class=\"text\"><strong>Serious Side Effects:<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p>Some people may develop serious lung problems, such as shortness of breath or pneumonia.<\/p>\n<p>Liver damage is possible, which may cause yellowing of the skin or dark urine.<\/p>\n<p>Rarely kidney damage can occur. In very rare cases, patients may experience swelling, low blood pressure, and fluid leakage from blood vessels into tissues.<\/p>\n<p>Swelling in the brain, seizures, or confusion are also possible, but only very rarely.<\/p>\n<p>Any severe reaction needs to be treated immediately, and the medicine discontinued.<\/p>\n<h2 class=\"wp-block-heading\"><strong>How Does It Work?<\/strong><\/h2>\n<p>Gemcitabine blocks the way cancer cells build DNA.<\/p>\n<p>Once administered into the body, it is metabolised into an active form that cancer cells misinterpret as genuine DNA building blocks.<\/p>\n<p>While trying to use this fake material, their DNA strand is killed. This stops the cells from dividing and kills them.<\/p>\n<p>As cancer cells grow faster than healthy cells, they take up more Gemcitabine and react more intensely to it.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Directions for Use<\/strong><\/h2>\n<p>Gemcitabine is not consumed or taken by mouth. It is always infused over a slow period into a vein.<\/p>\n<p>Each session lasts approximately 30 minutes. The number of days and frequency of administration depends on the type of cancer.<\/p>\n<p>For example, it could be given weekly for three weeks, followed by a week respite.<\/p>\n<p>The regimen can be modified by the doctor based on blood test results, side effects, and the progression of the cancer.<\/p>\n<p>Patients need to follow appointment schedules rigidly for the best outcomes.<\/p>\n<h2 class=\"wp-block-heading\"><strong>When Not to Use<\/strong><\/h2>\n<p>Low white counts (myelosuppression)<\/p>\n<p>Active, serious infection<\/p>\n<p>Severe kidney or liver disease (decreases drug clearance)<\/p>\n<p>Known hypersensitivity to Gemcitabine or its components<\/p>\n<h2 class=\"wp-block-heading\"><strong>Drug Interactions<\/strong><\/h2>\n<p>Avoid live vaccines while on treatment schedule (e.g., MMR, varicella) because of immunosuppression.<\/p>\n<p>May interact with other chemotherapy medications; will be closely monitored by your oncology team.<\/p>\n<p>Avoid NSAIDs (e.g., aspirin,\u00a0<a href=\"https:\/\/www.actizapharma.com\/product\/ibuprofen-tablets\/\" data-type=\"link\" data-id=\"https:\/\/www.actizapharma.com\/product\/ibuprofen-tablets\/\">ibuprofen<\/a>) if fever might be suppressed.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Safety Advice<\/strong><\/h2>\n<p>Avoid contact with those who are unwell or have just had vaccinations. Use good birth control throughout and following the treatment.<\/p>\n<p>Avoid fathering a child for a few months. Monitor blood, liver, and kidney function regularly\u2014report in case of fever, abnormal bleeding, or difficulty breathing.<\/p>\n<h2 class=\"wp-block-heading\"><strong>General Instructions<\/strong><\/h2>\n<p>Patients must return regularly for blood tests during treatment. This helps doctors keep track of white cells, red cells, and platelets.<\/p>\n<p>If you become ill, feverish, or experience bleeding, notify at once. Do not miss doses or taper off without consulting your doctor.<\/p>\n<p>Cover your skin with bandages to prevent cuts, and do not use a regular toothbrush or regular razor.<\/p>\n<p>Use birth control during treatment and for several months after treatment to prevent harm to an unborn child.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Special Dietary \/ Lifestyle Advice<\/strong><\/h2>\n<p>Stay hydrated by drinking plenty of water. This enables your kidneys to excrete the drug from your body.<\/p>\n<p>Consume light meals and a balanced diet to avoid weakness and nausea.<\/p>\n<p>Try to avoid alcohol, if possible, since it may also strain your liver further.<\/p>\n<p>Rest in good time and avoid crowds to avoid infection.<\/p>\n<p>Apply sunscreen when outdoors since your skin may be more sensitive due to chemotherapy.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Comparison with Other Treatments<\/strong><\/h2>\n<p>Compared to previous chemotherapy drugs, Gemcitabine is usually better tolerated.<\/p>\n<p>It causes fewer episodes of nausea and vomiting than some of them.<\/p>\n<p>Using Gemcitabine, for example, in combination with cisplatin or carboplatin, is more effective for certain types of lung or ovarian cancer.<\/p>\n<p>It\u2019s often chosen when the cancer has returned or spread, especially when patients need a milder one.<\/p>\n<p>Gemcitabine is more targeted in its assault on cancer cell DNA than certain older medications, and this could result in fewer total side effects.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Precautions &amp; Warnings<\/strong><\/h2>\n<p>Pregnancy and lactation are contraindicated. Use effective contraception before, during, and after therapy.<\/p>\n<p>Monitor disease and laboratory tests regularly.<\/p>\n<p>Withhold Gemcitabine upon the development of serious adverse effects (e.g.,\u00a0<a href=\"https:\/\/www.physio-pedia.com\/Post-Operative_Pulmonary_Complication\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" data-type=\"link\" data-id=\"https:\/\/www.physio-pedia.com\/Post-Operative_Pulmonary_Complication\">pulmonary complications<\/a>, neurologic, bleeding, increased risk of infection).<\/p>\n<h2 class=\"wp-block-heading\"><strong>Can It Be Used With Other Medications?<\/strong><\/h2>\n<div id=\"ilbIconList-2fa9725c-d\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-star-of-david\"><\/i>\n<p class=\"text\"><strong>Can be safely used with:<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div id=\"ilbIconList-a6fcd5dd-d\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-arrows-turn-right\"><\/i>\n<p class=\"text\"><strong>Platinum drugs:<\/strong>\u00a0cisplatin, carboplatin \u2013 effective in lung, ovarian, and bladder cancers<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrows-turn-right\"><\/i>\n<p class=\"text\"><strong>Taxanes:<\/strong>\u00a0paclitaxel (albumin-bound) for metastatic breast cancer<\/p>\n<\/li>\n<li class=\"list\"><i class=\"icon fa-solid fa-arrows-turn-right\"><\/i>\n<p class=\"text\"><strong>Antimetabolites:<\/strong>\u00a0FOLFOX or fluorouracil combinations in solid tumours<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div id=\"ilbIconList-23a308bf-6\" class=\"wp-block-ilb-icon-list  align\">\n<div class=\"ilbIconList left\">\n<ul class=\"lists\">\n<li class=\"list\"><i class=\"icon fa-solid fa-star-of-david\"><\/i>\n<p class=\"text\"><strong>Avoid with:<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p>NSAIDs can mask signs of infection when fever is a risk factor.<\/p>\n<p>Live vaccines, highly marrow-suppressive chemotherapy drugs, or drugs with overlapping toxicities.<\/p>\n<h2 class=\"wp-block-heading\"><strong>Storage<\/strong><\/h2>\n<p>Gemcitabine vials are stored under controlled conditions in the hospital or clinic and not at home.<\/p>\n<p>Preparatory solutions are used immediately or stored in accordance with drug guidelines prior to infusion.<\/p>\n","protected":false},"excerpt":{"rendered":"<table class=\"shop_attributes table mt-2 align-middle\">\n<tbody>\n<tr>\n<th class=\"table-light\">Product\/Composition:-<\/th>\n<td class=\"p-2\"><em>Gemcitabine Hydrochloride Injection<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Strength:-<\/th>\n<td class=\"p-2\"><em>1000mg<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Form:-<\/th>\n<td class=\"p-2\"><em>Injection<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Production Capacity:-<\/th>\n<td class=\"p-2\"><em>1 Million Injection\/Month<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Therapeutic use:-<\/th>\n<td class=\"p-2\"><em>Anti Cancer<\/em><\/td>\n<\/tr>\n<tr>\n<th class=\"table-light\">Package Insert\/Leaflet:-<\/th>\n<td class=\"p-2\"><em>Available upon request<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":8682,"comment_status":"open","ping_status":"closed","template":"","meta":{"inline_featured_image":false},"product_brand":[],"product_cat":[15,91,113],"product_tag":[157],"class_list":{"0":"post-8681","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-all-medicine","7":"product_cat-anti-cancer-drugs","8":"product_cat-injection-anti-cancer-drugs","9":"product_tag-injection","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/healaxispharma.com\/index.php?rest_route=\/wp\/v2\/product\/8681","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healaxispharma.com\/index.php?rest_route=\/wp\/v2\/product"}],"about":[{"href":"https:\/\/healaxispharma.com\/index.php?rest_route=\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8681"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=\/wp\/v2\/media\/8682"}],"wp:attachment":[{"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8681"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_brand&post=8681"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_cat&post=8681"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/healaxispharma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_tag&post=8681"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}